Advances in Applied Microbiology, Vol. 19 - download pdf or read online

By D. Perlman (Ed.)

ISBN-10: 0120026198

ISBN-13: 9780120026197

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Extra resources for Advances in Applied Microbiology, Vol. 19

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McKay, B. , Tytell, A. , and Charney, J. (1954). Antibiot. Chemother. 4, 259-261. , Rightsel, W. , Sloan, B. , French, J. , Bartz, Q. , and Dixon, G. J. (1963). Nature (London) 200, 1338-1339, Miller, I. , Stapley, E. , and Chaiet, L. (1962). Bacteriol. Proc. p. A49. , Boeck, L. , Hamill, R. , Higgens, C. , Hoehn, PRODUCTION OF SAME ANTIBIOTICS BY DIFFERENT GENERA 45 M. , Start, W. , and Whitney, J. G. (1971). J. Amer. Chem. SOC. 93, 2308-2310. Nakamura, G. (1961). J. , Ser. A 14, 94-97. , Molloy, B.

2-Acetamidophenoxazine-3-oneis a yellow pigment with mild antibiotic activity against some gram-positive bacteria, including some Actinomycetales, and some dermatophytes. , 1972). The actinomycins constitute a family of red antibiotics which share a phenoxazinone nucleus to which are attached two cyclic polypeptides. The structure of the polypeptides differs from one actinomycin to another. In Fig. 5, R1,R,, R,, and R, stand for various amino acid substitutents which differentiate one actinomycin from another.

The toxicity of this compound, which has no antibiotic activity under anerobic conditions, is probably due to the production of hydrogen peroxide, a strong poison for catalasedeficient organisms. Yeasts, which are rich in catalase, are not affected by toxoflavin. Xanthothricin, an antibiotic produced by a species of Streptomyces, closely related to S . , 1961). In addition, toxoflavin is similar to fer- 32 HUBERT A. , 1960). C. PRODICININES (Fig. 3 ) Prodigiosin is a tripyrrolic red antibiotic pigment characteristic of Serratia marcescens ( Williams and Hearn, 1967; Gaughran, 1969).

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Advances in Applied Microbiology, Vol. 19 by D. Perlman (Ed.)


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